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Nuclear Institute Vinca
Laboratory for Radiobiology and Molecular Genetics

 Contact data
StreetMike Petrovica Alasa 12-14 
ZIP, City, State 11001 - Belgrade (Serbia) 
Phone+ 381 11 245 82 22 - 686 
Fax+ 381 11 244 74 85 
Emailkrtolica@vin.bg.ac.rs 
 Contact person

Dr. Koviljka Krtolica Zikic (Senior Research Fellow)
 Activities in Research and Development

 RTD sectors:
» Bio technology     
» Diagnostics     
» Pharmaceutics     
 RTD Experiences

 Description of RTD activities
K-ras, hypermethylation of p15, p16 and MGMT genes, translocation, bcl2/JH t(14,18), bcr/abl t(9,22), leukemia, colorectal carcinoma.

Application of molecular oncogenetic in medicine. Analysis of:-Oncogene mutation (ras) and methylation as epigenetic modification of CpGs islands in the gene promoter region (p15
p16
MGMT in patients with leukemia or colorectal carcinomas.-Bcl2/JH t(14
18) translocation in patients with Non-Hodgkin Lymphoma
-Bcr/abl t(9
22) translocation in patients with Chronic Myeloid Leukemia and after bone marrow transplantation.

 Experiences in international Programmes
Six months (1979/1980) as visiting fellow at Colchester University, Essex, England (prof. David Rickwood)

 Inserted / Updated
2005-11-01 / 2008-11-27